Sunday, November 27, 2011

Pharmacological Therapy with Lifestyle Changes


Hay fever, the chronic condition that affects millions worldwide, is characterized by the hypersensitivity reaction to airborne allergens and the inflammation associated. This inflammation of the upper respiratory tract leads to symptoms of nasal congestion, sneezing, watery itchy eyes, and rhinitis. These symptoms plague those who suffer from this illness seasonally, perennially, or both. Standard treatment implemented on patients usually consists of pharmaceutical interventions in combination with lifestyle changes. With information used from this blog and through the website www.RateADrug.com, I was able to compare the medications evaluated to see effectiveness of hay fever management. The top five drugs evaluated for the indicated use of hay fever were Dimetapp Allergy, Benadryl Allergy Sinus, Vick’s Children’s NyQuil, Allegra, and Zyrtec. All of these drugs had high ratings for effectiveness and generally low side effects. The last three medications had the most side effects with overall theme being drowsiness. Through these evaluations, it should be recognized that all medications were either had an antihistamine as an active ingredient. This makes sense for the fact that one of the main components of the hypersensitivity reaction in hay fever revolves around the mast cell degranulation and histamine release. Through this mechanism of action, the risk of having many harmful side effects is low. Other medications, which was discussed in previous blogs, include decongestants, LTRAs, corticosteroids etc. Many of these are not as easily accessible because medications such as these usually either need to be bought through the pharmacy or through a prescription. Although these medications do appear to work well for those suffering, lifestyle changes a considered to be the first line defense. This is done primarily through avoiding the specific allergy triggers. Avoiding triggers has also been discussed in previous blogs with information regarding frequent dusting, using the air conditioning as opposed to keeping windows open etc. The reasoning for these interventions to help with the management of hay fever symptoms relates to the basic pathophysiology of the condition. By preventing the allergen, or antigen, from entering eyes and nasal passageway, the body would not produce the inflammatory effects. However this is easier said than done, that's why medication therapy is implemented in order to make up for what can be avoided. The use of these lifestyle changes also benefit the quality of life work optimally by creating a balance of the pharmacological therapies.  Although hay fever tends to be undertreated or self-treated by the patients, it is the goal for the health care providers to find a balance between this in order to promote better health and a better quality of life. 

Saturday, November 19, 2011

Spring Allergies vs Fall Allergies: Which is Worse


For those who suffer from seasonal symptoms of hay fever, there always seems to be that time of the year that is absolutely dreaded. For some it includes the spring, and for others it’s the fall. Seasonal allergy sufferers may also suffer from both or even more seasons, but one will usually dominate. So which is worse? Well, it depends on the specific allergen and when it is most abundant in the regional area at a specific time of the year.

Spring Allergies- Spring appears to be the time of the year when trees release the most pollen. Some of the top trees responsible for this abundant pollen release are Oak, Sycamore, Maple, Elm, Birch, Walnut, Hickory, and Cypress. The warming of the weather still accompanied by heavy winds also aggravates these allergens. Mold is still a prime allergy source in the spring, however it will worsen in the fall.
Oak Tree


Fall Allergies- The biggest culprit during the fall season is ragweed. Ragweed begins to pollinate in August normally, which makes it stay in the air and “attack” those for the following months. It’s also a very light particle that travels well in the wind. This allows it to act as an allergen to many nationwide, even if you don’t live near growing ragweed. Also in the fall, mold proliferates the most. Although mold is stated to be a major contributor to spring allergies, fall has higher levels because of the increase in spore release. The release of these mold spores also wreaks havoc to those susceptible to mold allergies. Another additional burden that fall allergies do play is with children. Because it is the start of the school year children will begin to have more exposure to certain school time activities, which may aggravate their allergies even further. This appears to be correlated with children asthma attack spikes in the fall as well.
Ragweed


So which one is worse? Well, of course, it changes for each individual because allergies are triggered by different allergens. For both spring and fall allergies, the best defense is avoiding the triggers in combination with medication in order to manage symptoms. These options were discussed in previous blogs.

Friday, November 11, 2011

The Typical Costs of Treatment


Depending on the severity of your condition, Hay Fever may end up being a relatively expensive disease with its chronic nature and pharmaceutical symptom management.

Let’s say you take a daily Claritin, Loratadine, 10mg 24 hr antihistamine is taken daily. For a box of 30 tablets, the regular price ranges about $19.89 at Target (and most drug stores). We can round this to about $20 a month for just a daily Claritin tablet and $240 a year.

Now let’s say you have multiple members of the family also taking this medication for their symptoms as well, this price will only go up and possibly double. But of course no medication is perfect and works for anyone. If you have congestion and decide that regular Claritin is sufficient and you need a decongestant, Claritin-D may be a more suitable choice, but with an added price. At Walgreens you can buy Claritin-D (120mg pseudoephedrine with 5mg loratadine antihistamine) 12-hour decongestant with 30 tablets for $29.89. The rounded cost for a day’s use of this drug will then be about $2. This would be $60 a month, and $720 a year if used two times a day, every day of the year.  Claritin-D, and other decongestants, such as Sudafed and Allegra-D are pose additional obstacles because you have to buy it over the counter which is an inconvenience.

Like I said before, Claritin or Claritin-D may not be the drug of choice for a particular user, others may prefer Allegra, Allegra-D, Zyrtec, and generic brands. However these are usually range around the same prices give or take a couple dollars.

Not only can these medications be expensive, but the other interventions taken by many allergy sufferers add up as well. These include things such as immunotherapy and lifestyle changes.
Immunotherapy prices tend to range on a variety of factors. These include length of therapy, type, and whether or not insurance will cover it. In the US, the average cost for immunotherapy ranged from $1,480-$2,500 for six years of therapy. This averaged to about $800 for the first, and most expensive year of therapy, and then dropped down to about $200-$300 dollars a year after that. This is an interesting consideration considering the outcomes of therapy hopefully mean eliminating drug usage for several years and when comparing this to some of the prices above this may be the more fiscally favorable choice.

Lastly, lifestyle changes do have a great financial impact on the hay fever sufferer as well. In previous entries. This includes using the air conditioning instead of opening windows, use of more cleaning products, and a higher quality of filtration system which may all increase electricity and gas bills. A common recommendation to those with hay fever is the use of a HEPA filter. The Envion Therapure Air Purifier for a Medium Room (26x8”) at target is sold online for $139.99. This only works for a room that is about 100-300sq ft. room, which means that multiple may need to be purchased to fulfill the needs of an individual with multiple rooms.


In conclusion, Hay Fever can add up to be a pretty expensive condition to have and something to keep in mind when choosing treatments.  However a combination of one or many may be necessary in order to ensure an improved quality of life which is priceless.



Saturday, November 5, 2011

How Big of a Problem is Hay Fever


It’s pretty obvious that Hay Fever is a big problem that affects many people worldwide. We know that it happens to children and adults and that we probably have a little of it (or a lot) ourselves. But really who all is suffering?

According to the CDC, the United States has had 17.7 million adults newly diagnosed with hay fever within the past 12 months and another 7.1 million children have reported having hay fever. The Revolution Health Group reports that hay fever causes about 14 million doctor office visits, 90% of which are seasonal and 70-80% have perennial as well. By the age 6-19, 17% of all children have an allergy to some environmental factor, and the severity and occurrence tend to greatly increase with age with no apparent discrimination to race or gender. Most importantly, the rates in the U.S. have been rising dramatically for unknown reasons.

So what does this even mean? That a significant number of people are suffering from hay fever and that this is an increasing problem. It appears that by this data alone that quality of life for these individuals is also affected. For example; for the doctor’s visits alone take into consideration the time, money (co-pays, medications, transportation etc.) and overall hassle of even getting the visits. This does not even include the symptomatic burdens associated with this chronic condition. Also, because having hay fever puts you at a higher risk for other hypersensitivity conditions from an overactive immune system, there is the increase for food/drug allergies, asthma, and other types of hypersensitivity reactions and the other issues that go along with them.

The most interesting thing about this condition is that even though it affects so many people, leads to so many undesirable effects, symptoms, medication usage, and even possible complications, there is no cure.